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But the GLP1 mechanism of action reaches beyond the pancreas, impacting other critical systems that make it an effective tool for managing type 2 diabetes and obesity

In a state where Gs activation is inhibited by pasireotide, a high glucose level could not stimulate GLP-1 secretion

Blog How does GLP-1 work for weight loss

The system also works to restore communication along the gut-brain axis by upregulating PYY and PPY genes, which create neuropeptides vital for clear and balanced hunger hormone signals